• Diosmin

• Hesperidin

Pharmacological Group:

Detralex belongs to the cardiovascular system class, specifically to agents that improve peripheral blood circulation. Scientifically, it is classified as a microcirculation-enhancing drug, also called an angioprotective. Detralex is part of the bioflavonoid group.

Physical Characteristics:

• 1000 mg tablets are large, film-coated tablets.

Chemical Composition:

• Each 1000 mg tablet contains: 900 mg diosmin and 100 mg hesperidin.

• Excipients may include: magnesium stearate, microcrystalline cellulose, sodium glycollate, gelatin, and talc.

• Film coating may contain: sodium lauryl sulfate, titanium dioxide, colorants (iron oxides – yellow and red), glycerin, hypromellose, magnesium stearate.

Mechanism of Action:

Diosmin and hesperidin help improve venous tone, reduce capillary irritation, and decrease swelling, thereby alleviating discomfort associated with venous insufficiency.

Therapeutic Indications:

Detralex 1000 mg tablets are indicated for:

• Chronic venous insufficiency of the lower limbs (functional and organic symptoms), including:

  • Heaviness in the legs, especially in the morning

  • Pain

  • Night cramps

• Symptomatic treatment of acute hemorrhoidal attacks

Dosage and Administration:

• Always consult a physician or pharmacist before starting and determining the dose.

• Chronic venous disease: 1 film-coated tablet daily (preferably in the morning with food).

• Acute hemorrhoidal attack:

  • First 4 days: 3 tablets daily (1 in the morning, 1 at lunch, 1 in the evening)

  • Next 3 days: 2 tablets daily

Contraindications:

• Hypersensitivity to active or excipient components

• Pregnancy and lactation: only use under medical supervision

Practical Recommendations:

• Tablets are large but have a break line for easier swallowing. Do not split or adjust the dose without physician instruction.

• Take with food to reduce gastrointestinal discomfort.

• Do not stop treatment prematurely; consult a physician if symptoms persist or improve.

Storage:

• Store at temperatures not exceeding 30°C

• Keep out of reach of children

• Do not use after the expiration date

Frequently Asked Questions:

• Can Detralex be taken on an empty stomach? No, it is recommended to take it with food.

• When will effects be noticeable? Symptom relief varies; some notice improvement in the first few days, others after several weeks.

• Can it be combined with other venotonics? Only under medical advice, based on your health history.

Where to Buy:

Available in licensed pharmacies in Georgia, including Pharmadepo, both in-store and online. Prices may vary depending on location and pharmacy promotions.