Anti-inflammatory vaginal suppositories help fight infections and regulate the natural flora.
Metronidazole, Miconazole
Obstetrics, Gynecology → Antiprotozoal, Antimicrobial, and Antifungal agents for local use
Vaginal suppository contains:
Active substances: Metronidazole 750mg, Miconazole nitrate 200mg.
Excipients: Hard fat (Witepsol S55).
Anti-infectives and antiseptics for gynecological use, Imidazole derivatives.
Vaginal candidiasis
Bacterial vaginosis
Trichomonal vaginitis
Vaginitis caused by mixed infections
1 suppository of the preparation is inserted intravaginally, at night, for 7 days.In cases of recurrent vaginitis or vaginitis resistant to other types of treatment, Limenda should be used for 14 days.Vaginal suppositories should be inserted deep into the vagina, using the single-use finger cots provided in the package.Elderly patients over 65 years of age do not require adjustment of the dosage regimen.
Hypersensitivity to the components of the medicine or other Imidazole derivatives
Severe liver function disorders
Epilepsy
Porphyria
First trimester of pregnancy
Rarely, hypersensitivity reactions (skin rash) and undesirable reactions such as increased fatigue, dizziness, headache, loss of appetite, nausea, vomiting, abdominal pain or cramps, metallic taste, vaginal itching, burning, and irritation of the vagina may occur.Due to inflammation of the vaginal mucosa during vaginitis, vaginal irritation (burning, itching) may increase after the insertion of the first suppository or on the third day of treatment. Such complications quickly disappear upon continuation of treatment. In case of severe irritation, treatment should be discontinued.
Pregnancy:The medicine can be used after the first trimester of pregnancy under a doctor's supervision, provided that the expected benefit to the mother outweighs the potential risk to the fetus.
Lactation:Breastfeeding should be discontinued during treatment, as Metronidazole passes into breast milk. Breastfeeding can be resumed 24–48 hours after the completion of treatment.
Fertility:There is no evidence of a negative impact on fertility when Metronidazole and Miconazole are used separately.
Data on the safety and efficacy of the medicine in children and adolescents under 18 years of age are not available.
